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Gene: Sgca (sarcoglycan, alpha) Rattus norvegicus
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Symbol: Sgca
Name: sarcoglycan, alpha
Description: Predicted to have calcium ion binding activity. Involved in response to denervation involved in regulation of muscle adaptation and skeletal muscle tissue regeneration. Predicted to localize to several cellular components, including the membrane raft; sarcoglycan complex; and sarcolemma. Biomarker of muscular atrophy. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2D and muscular dystrophy. Orthologous to human SGCA (sarcoglycan alpha); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adhalin; alpha-sarcoglycan; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); sarcoglycan, alpha (dystrophin-associated glycoprotein)
Orthologs:
Homo sapiens (human) : SGCA (sarcoglycan alpha)  HGNC  Alliance
Mus musculus (house mouse) : Sgca (sarcoglycan, alpha (dystrophin-associated glycoprotein))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sgca (sarcoglycan alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : SGCA (sarcoglycan alpha)
Canis lupus familiaris (dog) : SGCA (sarcoglycan alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sgca (sarcoglycan alpha)
Sus scrofa (pig) : SGCA (sarcoglycan alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01082,770,905 - 82,785,142 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01082,588,479 - 82,602,338 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,647,336 - 83,660,800 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11083,661,715 - 83,672,179 (-)NCBI
Celera1078,683,427 - 78,697,425 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sgca
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308062
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.