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Gene: E2f8 (E2F transcription factor 8) Rattus norvegicus
Symbol: E2f8
Name: E2F transcription factor 8
CRRD ID: 1308091
Description: Predicted to have several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in several processes, including hepatocyte differentiation; regulation of cellular macromolecule biosynthetic process; and trophoblast giant cell differentiation. Predicted to localize to RNA polymerase II transcription regulator complex; cytosol; and nuclear lumen. Orthologous to human E2F8 (E2F transcription factor 8); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E2F-8; LOC308607; RGD1308091; similar to hypothetical protein FLJ23311; transcription factor E2F8
Homo sapiens (human) : E2F8 (E2F transcription factor 8)  HGNC  Alliance
Mus musculus (house mouse) : E2f8 (E2F transcription factor 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E2f8 (E2F transcription factor 8)
Pan paniscus (bonobo/pygmy chimpanzee) : E2F8 (E2F transcription factor 8)
Canis lupus familiaris (dog) : E2F8 (E2F transcription factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E2f8 (E2F transcription factor 8)
Sus scrofa (pig) : E2F8 (E2F transcription factor 8)
Chlorocebus sabaeus (African green monkey) : E2F8 (E2F transcription factor 8)
Heterocephalus glaber (naked mole-rat) : E2f8 (E2F transcription factor 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01104,185,436 - 104,203,683 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1104,187,100 - 104,202,591 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01105,245,743 - 105,261,113 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4198,640,381 - 98,694,764 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1198,718,495 - 98,763,993 (-)NCBI
Celera192,773,529 - 92,791,422 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on E2f8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308091
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-09-15
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.