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Gene: E2f8 (E2F transcription factor 8) Rattus norvegicus
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Symbol: E2f8
Name: E2F transcription factor 8
Description: Predicted to have several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; protein homodimerization activity; and transcription corepressor activity. Predicted to be involved in several processes, including hepatocyte differentiation; regulation of cellular macromolecule biosynthetic process; and trophoblast giant cell differentiation. Predicted to localize to the RNA polymerase II transcription factor complex; cytosol; and nucleolus. Orthologous to human E2F8 (E2F transcription factor 8); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: E2F-8; LOC308607; RGD1308091; similar to hypothetical protein FLJ23311; transcription factor E2F8
Orthologs:
Homo sapiens (human) : E2F8 (E2F transcription factor 8)  HGNC  Alliance
Mus musculus (house mouse) : E2f8 (E2F transcription factor 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E2f8 (E2F transcription factor 8)
Pan paniscus (bonobo/pygmy chimpanzee) : E2F8 (E2F transcription factor 8)
Canis lupus familiaris (dog) : E2F8 (E2F transcription factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E2f8 (E2F transcription factor 8)
Sus scrofa (pig) : E2F8 (E2F transcription factor 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01104,185,436 - 104,203,683 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01105,245,743 - 105,261,113 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4198,640,381 - 98,694,764 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1198,718,495 - 98,763,993 (-)NCBI
Celera192,773,529 - 92,791,422 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on E2f8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308091
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.