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Gene: Gmnn (geminin, DNA replication inhibitor) Rattus norvegicus
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Symbol: Gmnn
Name: geminin, DNA replication inhibitor
Description: Predicted to have several functions, including histone deacetylase binding activity; repressing transcription factor binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including DNA replication preinitiation complex assembly; negative regulation of cellular macromolecule biosynthetic process; and positive regulation of chromatin binding activity. Predicted to localize to the cytosol and nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 6. Orthologous to human GMNN (geminin DNA replication inhibitor); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: geminin; LOC291137
Orthologs:
Homo sapiens (human) : GMNN (geminin DNA replication inhibitor)  HGNC  Alliance
Mus musculus (house mouse) : Gmnn (geminin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gmnn (geminin DNA replication inhibitor)
Pan paniscus (bonobo/pygmy chimpanzee) : GMNN (geminin DNA replication inhibitor)
Canis lupus familiaris (dog) : GMNN (geminin DNA replication inhibitor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gmnn (geminin DNA replication inhibitor)
Sus scrofa (pig) : GMNN (geminin DNA replication inhibitor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01742,302,523 - 42,310,783 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01744,170,109 - 44,178,377 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41747,372,316 - 47,380,559 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11747,375,179 - 47,383,393 (+)NCBI
Celera1739,938,690 - 39,946,933 (+)NCBICelera
Cytogenetic Map17p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gmnn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308137
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.