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Gene: Tbx21 (T-box transcription factor 21) Rattus norvegicus
Symbol: Tbx21
Name: T-box transcription factor 21
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II activating transcription factor binding activity; and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including heart looping; regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; and regulation of transcription by RNA polymerase II. Predicted to localize to neuronal cell body and nucleus. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance. Orthologous to human TBX21 (T-box transcription factor 21); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-27 signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; acetamide; amphetamine.
Type: protein-coding
Also known as: LOC303496; T-box 21; T-box transcription factor TBX21
Homo sapiens (human) : TBX21 (T-box transcription factor 21)  HGNC  Alliance
Mus musculus (house mouse) : Tbx21 (T-box 21)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx21 (T-box transcription factor 21)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX21 (T-box transcription factor 21)
Canis lupus familiaris (dog) : TBX21 (T-box transcription factor 21)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx21 (T-box transcription factor 21)
Sus scrofa (pig) : TBX21 (T-box transcription factor 21)
Chlorocebus sabaeus (African green monkey) : TBX21 (T-box transcription factor 21)
Heterocephalus glaber (naked mole-rat) : Tbx21 (T-box transcription factor 21)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01085,032,799 - 85,049,331 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1085,032,799 - 85,049,331 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01084,822,665 - 84,839,295 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41085,817,743 - 85,834,178 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11085,832,581 - 85,865,421 (-)NCBI
Celera1080,842,416 - 80,858,935 (-)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tbx21
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308264
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.