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Gene: Wars1 (tryptophanyl-tRNA synthetase 1) Rattus norvegicus
Symbol: Wars1
Name: tryptophanyl-tRNA synthetase 1
Description: Predicted to have several functions, including kinase inhibitor activity; protein homodimerization activity; and tryptophan-tRNA ligase activity. Predicted to be involved in several processes, including regulation of angiogenesis; regulation of protein modification process; and tryptophanyl-tRNA aminoacylation. Predicted to localize to cytosol; nucleus; and protein-containing complex. Human ortholog(s) of this gene implicated in distal hereditary motor neuronopathy type 9. Orthologous to human WARS1 (tryptophanyl-tRNA synthetase 1); PARTICIPATES IN tryptophan metabolic pathway; aminoacyl-tRNA biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC314442; trpRS; tryptophan--tRNA ligase; tryptophan--tRNA ligase, cytoplasmic; tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase, cytoplasmic; Wars
Homo sapiens (human) : WARS1 (tryptophanyl-tRNA synthetase 1)  HGNC  Alliance
Mus musculus (house mouse) : Wars (tryptophanyl-tRNA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wars1 (tryptophanyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : WARS1 (tryptophanyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : WARS1 (tryptophanyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wars1 (tryptophanyl-tRNA synthetase 1)
Sus scrofa (pig) : WARS1 (tryptophanyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : WARS1 (tryptophanyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Wars1 (tryptophanyl-tRNA synthetase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06132,771,026 - 132,802,262 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,771,021 - 132,802,210 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,941,102 - 141,972,312 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46133,200,866 - 133,232,048 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16133,207,052 - 133,238,235 (-)NCBI
Celera6125,326,985 - 125,358,157 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Wars1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308278
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.