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Gene: Ikbke (inhibitor of nuclear factor kappa B kinase subunit epsilon) Rattus norvegicus
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Symbol: Ikbke
Name: inhibitor of nuclear factor kappa B kinase subunit epsilon
Description: Predicted to have several functions, including IkappaB kinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and NF-kappaB-inducing kinase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; positive regulation of signal transduction; and response to type I interferon. Predicted to localize to the PML body and mitochondrial membrane. Orthologous to human IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 1-naphthyl isothiocyanate; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of kappaB kinase epsilon; inhibitor of nuclear factor kappa-B kinase subunit epsilon; LOC363984
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01348,031,325 - 48,056,394 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1348,031,410 - 48,056,394 (-)Ensembl
Rnor_5.01353,107,093 - 53,132,162 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41344,197,625 - 44,222,609 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11344,211,668 - 44,233,796 (-)NCBI
Celera1343,057,856 - 43,082,833 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ikbke
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308352
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.