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Gene: Trio (trio Rho guanine nucleotide exchange factor) Rattus norvegicus
Symbol: Trio
Name: trio Rho guanine nucleotide exchange factor
Description: Exhibits enzyme binding activity. Predicted to be involved in negative regulation of fat cell differentiation. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 44. Orthologous to human TRIO (trio Rho guanine nucleotide exchange factor); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC310192; triple functional domain (PTPRF interacting); triple functional domain protein
Homo sapiens (human) : TRIO (trio Rho guanine nucleotide exchange factor)  HGNC  Alliance
Mus musculus (house mouse) : Trio (triple functional domain (PTPRF interacting))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trio (trio Rho guanine nucleotide exchange factor)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIO (trio Rho guanine nucleotide exchange factor)
Canis lupus familiaris (dog) : TRIO (trio Rho guanine nucleotide exchange factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trio (trio Rho guanine nucleotide exchange factor)
Sus scrofa (pig) : TRIO (trio Rho guanine nucleotide exchange factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0280,471,398 - 80,769,313 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02100,137,355 - 100,437,964 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4279,634,843 - 79,832,549 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1279,581,604 - 79,878,530 (-)NCBI
Celera274,141,588 - 74,436,556 (-)NCBICelera
Cytogenetic Map2q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Trio
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308360
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.