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Gene: Samhd1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1) Rattus norvegicus
Symbol: Samhd1
Name: SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
Description: Predicted to have several functions, including dGTP binding activity; dGTPase activity; and nucleic acid binding activity. Predicted to be involved in several processes, including DNA metabolic process; nucleobase-containing compound catabolic process; and protein homotetramerization. Predicted to localize to the nucleoplasm; site of double-strand break; and tetraspanin-enriched microdomain. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome and Chilblain lupus. Orthologous to human SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; sodium dichromate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deoxynucleoside triphosphate triphosphohydrolase SAMHD1; LOC311580; SAM domain and HD domain, 1; SAM domain and HD domain-containing protein 1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03153,210,829 - 153,250,705 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03158,468,644 - 158,504,183 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43147,689,421 - 147,727,429 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13147,595,329 - 147,627,065 (-)NCBI
Celera3144,468,270 - 144,500,913 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Samhd1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308369
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.