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Gene: Muc16 (mucin 16, cell surface associated) Rattus norvegicus
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Symbol: Muc16
Name: mucin 16, cell surface associated
Description: Predicted to be involved in negative regulation of epithelial cell proliferation; negative regulation of interleukin-6 biosynthetic process; and negative regulation of wound healing. Localizes to the extracellular space. Biomarker of ovarian carcinoma. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human MUC16 (mucin 16, cell surface associated); INTERACTS WITH 17beta-estradiol; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC315451; mucin 16; mucin-16; RGD1308422; similar to ovarian cancer related tumor marker CA125
Orthologs:
Homo sapiens (human) : MUC16 (mucin 16, cell surface associated)  HGNC  Alliance
Mus musculus (house mouse) : Muc16 (mucin 16)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Muc16 (mucin 16, cell surface associated)
Pan paniscus (bonobo/pygmy chimpanzee) : MUC16 (mucin 16, cell surface associated)
Canis lupus familiaris (dog) : LOC476718 (mucin-16)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Muc16 (mucin 16, cell surface associated)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0818,438,838 - 18,639,777 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0818,505,745 - 18,678,475 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4816,552,167 - 16,726,561 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1816,552,166 - 16,813,582 (-)NCBI
Celera817,583,127 - 17,786,039 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Muc16
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308422
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.