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Gene: Dennd4c (DENN domain containing 4C) Rattus norvegicus
Symbol: Dennd4c
Name: DENN domain containing 4C
Description: Predicted to have Rab guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to insulin stimulus and protein localization to plasma membrane. Predicted to localize to the cytoplasm; plasma membrane; and retromer complex. Orthologous to human DENND4C (DENN domain containing 4C); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: DENN domain-containing protein 4C; DENN/MADD domain containing 4C; LOC313340; RGD1308489; similar to hypothetical protein
Homo sapiens (human) : DENND4C (DENN domain containing 4C)  HGNC  Alliance
Mus musculus (house mouse) : Dennd4c (DENN/MADD domain containing 4C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dennd4c (DENN domain containing 4C)
Pan paniscus (bonobo/pygmy chimpanzee) : DENND4C (DENN domain containing 4C)
Canis lupus familiaris (dog) : DENND4C (DENN domain containing 4C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dennd4c (DENN domain containing 4C)
Sus scrofa (pig) : DENND4C (DENN domain containing 4C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05105,100,081 - 105,195,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05109,085,833 - 109,182,502 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45106,090,415 - 106,162,420 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15106,090,717 - 106,167,026 (+)NCBI
Celera5101,714,237 - 101,809,916 (-)NCBICelera
Cytogenetic Map5q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dennd4c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308489
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.