Gene: Nkx2-3 (NK2 homeobox 3) Rattus norvegicus
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Symbol: Nkx2-3
Name: NK2 homeobox 3
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity; predicted to be involved in several processes, including animal organ development, leukocyte homeostasis, and leukocyte migration; predicted to localize to the nucleus; orthologous to human NKX2-3 (NK2 homeobox 3); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homeobox protein Nkx-2.3; LOC309389; NK2 transcription factor related, locus 3; NK2 transcription factor related, locus 3 (Drosophila)
Orthologs:
Homo sapiens (human) : NKX2-3 (NK2 homeobox 3)  HGNC  Alliance
Mus musculus (house mouse) : Nkx2-3 (NK2 homeobox 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkx2-3 (NK2 homeobox 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NKX2-3 (NK2 homeobox 3)
Canis lupus familiaris (dog) : NKX2-3 (NK2 homeobox 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkx2-3 (NK2 homeobox 3)
Sus scrofa (pig) : NKX2-3 (NK2 homeobox 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01263,361,238 - 263,371,043 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01270,812,400 - 270,815,353 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41247,221,087 - 247,224,040 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11247,335,943 - 247,338,696 (-)NCBI
Celera1238,299,219 - 238,302,172 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nkx2-3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308521
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.