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Gene: Tmc1 (transmembrane channel-like 1) Rattus norvegicus
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Symbol: Tmc1
Name: transmembrane channel-like 1
Description: Predicted to have mechanosensitive ion channel activity and voltage-gated calcium channel activity. Predicted to be involved in several processes, including auditory receptor cell development; detection of mechanical stimulus involved in sensory perception of sound; and vestibular reflex. Predicted to localize to external side of plasma membrane and stereocilium tip. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 36; autosomal recessive nonsyndromic deafness 7; and sensorineural hearing loss. Orthologous to human TMC1 (transmembrane channel like 1); INTERACTS WITH bisphenol A; furan; 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC361739; transmembrane channel-like gene family 1; transmembrane channel-like protein 1
Orthologs:
Homo sapiens (human) : TMC1 (transmembrane channel like 1)  HGNC  Alliance
Mus musculus (house mouse) : Tmc1 (transmembrane channel-like gene family 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmc1 (transmembrane channel like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TMC1 (transmembrane channel like 1)
Canis lupus familiaris (dog) : TMC1 (transmembrane channel like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmc1 (transmembrane channel like 1)
Sus scrofa (pig) : TMC1 (transmembrane channel like 1)
Chlorocebus sabaeus (African green monkey) : TMC1 (transmembrane channel like 1)
Heterocephalus glaber (naked mole-rat) : Tmc1 (transmembrane channel like 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01238,336,919 - 238,525,792 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,336,919 - 238,441,500 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01245,633,195 - 245,678,137 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01245,706,178 - 245,816,628 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,911,499 - 224,108,034 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11224,075,517 - 224,193,990 (-)NCBI
Celera1215,544,754 - 215,710,467 (-)NCBICelera
Cytogenetic Map1q51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tmc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308682
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.