Gene: Spred1 (sprouty-related, EVH1 domain containing 1) Rattus norvegicus
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Symbol: Spred1
Name: sprouty-related, EVH1 domain containing 1
Description: Predicted to have enzyme binding activity, protein serine/threonine kinase inhibitor activity, and stem cell factor receptor binding activity; predicted to be involved in several processes, including negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of cellular metabolic process, and positive regulation of DNA damage response, signal transduction by p53 class mediator; predicted to colocalize with the cytoplasmic vesicle; orthologous to human SPRED1 (sprouty related EVH1 domain containing 1); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC296072; sprouty protein with EVH-1 domain 1, related sequence; sprouty-related, EVH1 domain-containing protein 1
Orthologs:
Homo sapiens (human) : SPRED1 (sprouty related EVH1 domain containing 1)  HGNC  Alliance
Mus musculus (house mouse) : Spred1 (sprouty protein with EVH-1 domain 1, related sequence)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spred1 (sprouty related EVH1 domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPRED1 (sprouty related EVH1 domain containing 1)
Canis lupus familiaris (dog) : SPRED1 (sprouty related EVH1 domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spred1 (sprouty related EVH1 domain containing 1)
Sus scrofa (pig) : SPRED1 (sprouty related EVH1 domain containing 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03108,795,337 - 108,861,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03115,352,442 - 115,418,428 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43103,184,312 - 103,246,353 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13103,080,539 - 103,145,109 (+)NCBI
Celera3102,913,163 - 102,974,986 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Spred1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308735
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.