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Gene: Spred1 (sprouty-related, EVH1 domain containing 1) Rattus norvegicus
Symbol: Spred1
Name: sprouty-related, EVH1 domain containing 1
Description: Predicted to have enzyme binding activity; protein serine/threonine kinase inhibitor activity; and stem cell factor receptor binding activity. Predicted to be involved in several processes, including negative regulation of cell migration involved in sprouting angiogenesis; negative regulation of phosphate metabolic process; and positive regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to colocalize with cytoplasmic vesicle. Orthologous to human SPRED1 (sprouty related EVH1 domain containing 1); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
Also known as: LOC296072; sprouty protein with EVH-1 domain 1, related sequence; sprouty-related, EVH1 domain-containing protein 1
Homo sapiens (human) : SPRED1 (sprouty related EVH1 domain containing 1)  HGNC  Alliance
Mus musculus (house mouse) : Spred1 (sprouty protein with EVH-1 domain 1, related sequence)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spred1 (sprouty related EVH1 domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPRED1 (sprouty related EVH1 domain containing 1)
Canis lupus familiaris (dog) : SPRED1 (sprouty related EVH1 domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spred1 (sprouty related EVH1 domain containing 1)
Sus scrofa (pig) : SPRED1 (sprouty related EVH1 domain containing 1)
Chlorocebus sabaeus (African green monkey) : SPRED1 (sprouty related EVH1 domain containing 1)
Heterocephalus glaber (naked mole-rat) : Spred1 (sprouty related EVH1 domain containing 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03108,795,337 - 108,861,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3108,795,235 - 108,857,556 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03115,352,442 - 115,418,428 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43103,184,312 - 103,246,353 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13103,080,539 - 103,145,109 (+)NCBI
Celera3102,913,163 - 102,974,986 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Spred1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308735
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.