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Gene: Ern2 (endoplasmic reticulum to nucleus signaling 2) Rattus norvegicus
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Symbol: Ern2
Name: endoplasmic reticulum to nucleus signaling 2
Description: Predicted to have several functions, including ATP binding activity; magnesium ion binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including IRE1-mediated unfolded protein response; apoptotic chromosome condensation; and intracellular signal transduction. Predicted to localize to the IRE1-TRAF2-ASK1 complex. Orthologous to human ERN2 (endoplasmic reticulum to nucleus signaling 2); INTERACTS WITH 17beta-estradiol; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endoplasmic reticulum (ER) to nucleus signalling 2; LOC365363; serine/threonine-protein kinase/endoribonuclease IRE2
Orthologs:
Homo sapiens (human) : ERN2 (endoplasmic reticulum to nucleus signaling 2)  HGNC  Alliance
Mus musculus (house mouse) : Ern2 (endoplasmic reticulum (ER) to nucleus signalling 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ern2 (endoplasmic reticulum to nucleus signaling 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ERN2 (endoplasmic reticulum to nucleus signaling 2)
Canis lupus familiaris (dog) : ERN2 (endoplasmic reticulum to nucleus signaling 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ern2 (endoplasmic reticulum to nucleus signaling 2)
Sus scrofa (pig) : ERN2 (endoplasmic reticulum to nucleus signaling 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01192,126,023 - 192,142,865 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01199,188,292 - 199,205,123 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,012,795 - 181,029,728 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11181,152,704 - 181,169,643 (-)NCBI
Celera1174,434,976 - 174,451,775 (-)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ern2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308743
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.