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Gene: Blm (BLM RecQ like helicase) Rattus norvegicus
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Symbol: Blm
Name: BLM RecQ like helicase
Description: Predicted to have several functions, including ATP binding activity; DNA binding activity; and helicase activity. Predicted to be involved in several processes, including DNA geometric change; DNA metabolic process; and regulation of nucleobase-containing compound metabolic process. Predicted to colocalize with the PML body and chromosome, telomeric region. Human ortholog(s) of this gene implicated in Bloom syndrome. Orthologous to human BLM (BLM RecQ like helicase); PARTICIPATES IN DNA replication pathway; homologous recombination pathway of double-strand break repair; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; all-trans-retinoic acid; dioxygen.
Type: protein-coding
RefSeq Status: MODEL
Also known as: Bloom syndrome; Bloom syndrome homolog; Bloom syndrome homolog (human); Bloom syndrome RecQ like helicase; Bloom syndrome, RecQ helicase-like; LOC308755
Orthologs:
Homo sapiens (human) : BLM (BLM RecQ like helicase)  HGNC  Alliance
Mus musculus (house mouse) : Blm (Bloom syndrome, RecQ like helicase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Blm (BLM RecQ like helicase)
Pan paniscus (bonobo/pygmy chimpanzee) : BLM (BLM RecQ like helicase)
Canis lupus familiaris (dog) : BLM (BLM RecQ like helicase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Blm (BLM RecQ like helicase)
Sus scrofa (pig) : BLM (BLM RecQ like helicase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01142,246,773 - 142,332,616 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01143,198,619 - 143,285,603 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,271,573 - 136,358,077 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11136,350,811 - 136,606,090 (-)NCBI
Celera1126,469,103 - 126,554,926 (-)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Blm
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308810
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.