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Gene: Mkks (McKusick-Kaufman syndrome) Rattus norvegicus
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Symbol: Mkks
Name: McKusick-Kaufman syndrome
Description: Predicted to have RNA polymerase II repressing transcription factor binding activity. Predicted to be involved in several processes, including brain development; regulation of actin filament organization; and regulation of blood vessel diameter. Predicted to localize to several cellular components, including microtubule organizing center; motile cilium; and nucleus. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 6; McKusick-Kaufman syndrome; congenital heart disease; and obesity. Orthologous to human MKKS (McKusick-Kaufman syndrome); INTERACTS WITH bisphenol A; flutamide; gentamycin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: LOC311456; McKusick-Kaufman syndrome protein; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; MGC95109
Orthologs:
Homo sapiens (human) : MKKS (McKusick-Kaufman syndrome)  HGNC  Alliance
Mus musculus (house mouse) : Mkks (McKusick-Kaufman syndrome)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mkks (McKusick-Kaufman syndrome)
Pan paniscus (bonobo/pygmy chimpanzee) : MKKS (McKusick-Kaufman syndrome)
Canis lupus familiaris (dog) : MKKS (McKusick-Kaufman syndrome)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mkks (McKusick-Kaufman syndrome)
Sus scrofa (pig) : MKKS (McKusick-Kaufman syndrome)
Chlorocebus sabaeus (African green monkey) : MKKS (McKusick-Kaufman syndrome)
Heterocephalus glaber (naked mole-rat) : Mkks (McKusick-Kaufman syndrome)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03129,866,542 - 129,885,213 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3129,866,545 - 129,884,810 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03136,347,547 - 136,365,815 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43124,975,099 - 124,993,345 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13124,880,674 - 124,898,918 (-)NCBI
Celera3122,920,784 - 122,939,041 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mkks
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308814
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.