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Gene: Mkks (McKusick-Kaufman syndrome) Rattus norvegicus
Symbol: Mkks
Name: McKusick-Kaufman syndrome
Description: Predicted to have RNA polymerase II repressing transcription factor binding activity. Predicted to be involved in several processes, including brain development; regulation of actin filament organization; and regulation of blood vessel diameter. Predicted to localize to several cellular components, including microtubule organizing center; motile cilium; and nucleus. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 6; McKusick-Kaufman syndrome; congenital heart disease; and obesity. Orthologous to human MKKS (McKusick-Kaufman syndrome); INTERACTS WITH bisphenol A; flutamide; gentamycin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: LOC311456; McKusick-Kaufman syndrome protein; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; MGC95109
Homo sapiens (human) : MKKS (McKusick-Kaufman syndrome)  HGNC  Alliance
Mus musculus (house mouse) : Mkks (McKusick-Kaufman syndrome)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mkks (McKusick-Kaufman syndrome)
Pan paniscus (bonobo/pygmy chimpanzee) : MKKS (McKusick-Kaufman syndrome)
Canis lupus familiaris (dog) : MKKS (McKusick-Kaufman syndrome)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mkks (McKusick-Kaufman syndrome)
Sus scrofa (pig) : MKKS (McKusick-Kaufman syndrome)
Chlorocebus sabaeus (African green monkey) : MKKS (McKusick-Kaufman syndrome)
Heterocephalus glaber (naked mole-rat) : Mkks (McKusick-Kaufman syndrome)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03129,866,542 - 129,885,213 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3129,866,545 - 129,884,810 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03136,347,547 - 136,365,815 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43124,975,099 - 124,993,345 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13124,880,674 - 124,898,918 (-)NCBI
Celera3122,920,784 - 122,939,041 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Mkks
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308814
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.