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Gene: Piezo1 (piezo-type mechanosensitive ion channel component 1) Rattus norvegicus
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Symbol: Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Description: Predicted to have cation channel activity; identical protein binding activity; and mechanosensitive ion channel activity. Predicted to be involved in several processes, including cellular response to mechanical stimulus; positive regulation of cell-cell adhesion mediated by integrin; and positive regulation of integrin activation. Predicted to localize to endoplasmic reticulum and plasma membrane. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 1 and hereditary lymphedema. Orthologous to human PIEZO1 (piezo type mechanosensitive ion channel component 1); INTERACTS WITH (+)-schisandrin B; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Fam38a; family with sequence similarity 38, member A; LOC361430; membrane protein induced by beta-amyloid treatment; Mib
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01955,305,494 - 55,367,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,305,496 - 55,367,353 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,014,939 - 66,075,869 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,770,967 - 52,834,347 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,776,154 - 52,852,837 (-)NCBI
Celera1949,784,059 - 49,845,831 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Piezo1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308822
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.