Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Lama2 (laminin subunit alpha 2) Rattus norvegicus
Symbol: Lama2
Name: laminin subunit alpha 2
CRRD ID: 1308889
Description: Predicted to have extracellular matrix structural constituent. Involved in Schwann cell differentiation. Localizes to basement membrane and dendritic spine. Biomarker of renovascular hypertension. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy; congenital merosin-deficient muscular dystrophy 1A; muscular dystrophy; and myopia. Orthologous to human LAMA2 (laminin subunit alpha 2); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; dilated cardiomyopathy pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: laminin subunit alpha-2; laminin, alpha 2; LOC309368
Homo sapiens (human) : LAMA2 (laminin subunit alpha 2)  HGNC  Alliance
Mus musculus (house mouse) : Lama2 (laminin, alpha 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lama2 (laminin subunit alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LAMA2 (laminin subunit alpha 2)
Canis lupus familiaris (dog) : LAMA2 (laminin subunit alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lama2 (laminin subunit alpha 2)
Sus scrofa (pig) : LAMA2 (laminin subunit alpha 2)
Chlorocebus sabaeus (African green monkey) : LAMA2 (laminin subunit alpha 2)
Heterocephalus glaber (naked mole-rat) : Lama2 (laminin subunit alpha 2)
more info ...
Allele / Splice: Lama2Tn(sb-T2/Bart3)2.2013Mcwi  
Genetic Models: F344-Lama2Tn(sb-T2/Bart3)2.2013Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0118,491,264 - 19,143,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl118,491,384 - 19,143,269 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0120,002,787 - 20,647,256 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4118,203,466 - 18,885,462 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1118,324,930 - 18,885,310 (+)NCBI
Celera116,078,601 - 16,724,118 (+)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Lama2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308889
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.