Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Large1 (LARGE xylosyl- and glucuronyltransferase 1) Rattus norvegicus
Analyze
Symbol: Large1
Name: LARGE xylosyl- and glucuronyltransferase 1
Description: Predicted to have glucuronosyltransferase activity; manganese ion binding activity; and xylosyltransferase activity. Predicted to be involved in several processes, including muscle cell cellular homeostasis; protein O-linked mannosylation; and skeletal muscle tissue regeneration. Predicted to localize to the Golgi apparatus. Human ortholog(s) of this gene implicated in Walker-Warburg syndrome and muscular dystrophy-dystroglycanopathy type B6. Orthologous to human LARGE1 (LARGE xylosyl- and glucuronyltransferase 1); INTERACTS WITH (+)-schisandrin B; acrylamide; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glycosyltransferase-like protein LARGE1; Large; like-glycosyltransferase; LOC361368
Orthologs:
Homo sapiens (human) : LARGE1 (LARGE xylosyl- and glucuronyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Large1 (LARGE xylosyl- and glucuronyltransferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Large1 (LARGE xylosyl- and glucuronyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LARGE1 (LARGE xylosyl- and glucuronyltransferase 1)
Canis lupus familiaris (dog) : LARGE1 (LARGE xylosyl- and glucuronyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Large1 (LARGE xylosyl- and glucuronyltransferase 1)
Sus scrofa (pig) : LARGE1 (LARGE xylosyl- and glucuronyltransferase 1)
more info ...
Allele / Splice: LargeTn(sb-T2/Bart3)2.336Mcwi  
Genetic Models: F344-LargeTn(sb-T2/Bart3)2.336Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01912,481,563 - 12,945,320 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01923,595,328 - 24,054,765 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41912,043,818 - 12,497,663 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11912,049,826 - 12,369,988 (-)NCBI
Celera1911,480,096 - 11,923,685 (-)NCBICelera
Cytogenetic Map19p12-p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Large1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308895
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.