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Gene: Nsd3 (nuclear receptor binding SET domain protein 3) Rattus norvegicus
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Symbol: Nsd3
Name: nuclear receptor binding SET domain protein 3
CRRD ID: 1308980
Description: Predicted to have histone-lysine N-methyltransferase activity and transcription coactivator activity. Predicted to be involved in histone methylation; positive regulation of histone H3-K36 trimethylation; and regulation of transcription, DNA-templated. Predicted to localize to chromatin and nucleus. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human NSD3 (nuclear receptor binding SET domain protein 3); PARTICIPATES IN histone modification pathway; lysine degradation pathway; INTERACTS WITH 17beta-estradiol; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: histone-lysine N-methyltransferase NSD3; LOC290831; Whsc1l1; Wolf-Hirschhorn syndrome candidate 1-like 1; Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
Orthologs:
Homo sapiens (human) : NSD3 (nuclear receptor binding SET domain protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Nsd3 (nuclear receptor binding SET domain protein 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nsd3 (nuclear receptor binding SET domain protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NSD3 (nuclear receptor binding SET domain protein 3)
Canis lupus familiaris (dog) : NSD3 (nuclear receptor binding SET domain protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nsd3 (nuclear receptor binding SET domain protein 3)
Sus scrofa (pig) : NSD3 (nuclear receptor binding SET domain protein 3)
Chlorocebus sabaeus (African green monkey) : NSD3 (nuclear receptor binding SET domain protein 3)
Heterocephalus glaber (naked mole-rat) : Nsd3 (nuclear receptor binding SET domain protein 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01671,126,276 - 71,237,118 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,130,668 - 71,237,118 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01670,786,828 - 70,897,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,733,902 - 70,839,802 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11670,734,444 - 70,806,495 (-)NCBI
Celera1664,268,667 - 64,374,056 (-)NCBICelera
Cytogenetic Map16q12.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nsd3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1308980
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.