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Gene: Ptch2 (patched 2) Rattus norvegicus
Symbol: Ptch2
Name: patched 2
Description: Predicted to have hedgehog family protein binding activity; hedgehog receptor activity; and smoothened binding activity. Predicted to be involved in several processes, including epidermal cell fate specification; positive regulation of epidermal cell differentiation; and smoothened signaling pathway. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in basal cell carcinoma; medulloblastoma; and nevoid basal cell carcinoma syndrome. Orthologous to human PTCH2 (patched 2); PARTICIPATES IN Hedgehog signaling pathway; INTERACTS WITH bisphenol A; C60 fullerene; 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC366452; patched homolog 1; patched homolog 2; patched homolog 2 (Drosophila); Ptch1
Homo sapiens (human) : PTCH2 (patched 2)  HGNC  Alliance
Mus musculus (house mouse) : Ptch2 (patched 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptch2 (patched 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTCH2 (patched 2)
Canis lupus familiaris (dog) : PTCH2 (patched 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptch2 (patched 2)
Sus scrofa (pig) : PTCH2 (patched 2)
Chlorocebus sabaeus (African green monkey) : PTCH2 (patched 2)
Heterocephalus glaber (naked mole-rat) : Ptch2 (patched 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05135,962,252 - 135,983,816 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,962,911 - 135,983,816 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,757,425 - 139,776,623 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,408,481 - 137,429,633 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15137,410,236 - 137,433,563 (+)NCBI
Celera5129,093,838 - 129,114,695 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ptch2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309039
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.