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Gene: Prmt5 (protein arginine methyltransferase 5) Rattus norvegicus
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Symbol: Prmt5
Name: protein arginine methyltransferase 5
Description: Predicted to have several functions, including p53 binding activity; protein-arginine N-methyltransferase activity; and sequence-specific DNA binding activity. Involved in several processes, including liver regeneration; positive regulation of oligodendrocyte differentiation; and regulation of ERK1 and ERK2 cascade. Localizes to protein-containing complex. Biomarker of asthma. Orthologous to human PRMT5 (protein arginine methyltransferase 5); PARTICIPATES IN histone modification pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HMT1 hnRNP methyltransferase-like 5; Hrmt1l5; LOC364382; protein arginine N-methyltransferase 5; Skb1; SKB1 homolog; SKB1 homolog (S. pombe)
Orthologs:
Homo sapiens (human) : PRMT5 (protein arginine methyltransferase 5)  HGNC  Alliance
Mus musculus (house mouse) : Prmt5 (protein arginine N-methyltransferase 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prmt5 (protein arginine methyltransferase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PRMT5 (protein arginine methyltransferase 5)
Canis lupus familiaris (dog) : PRMT5 (protein arginine methyltransferase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prmt5 (protein arginine methyltransferase 5)
Sus scrofa (pig) : PRMT5 (protein arginine methyltransferase 5)
Chlorocebus sabaeus (African green monkey) : PRMT5 (protein arginine methyltransferase 5)
Heterocephalus glaber (naked mole-rat) : Prmt5 (protein arginine methyltransferase 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01533,156,508 - 33,165,893 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,156,492 - 33,165,895 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,041,740 - 37,051,125 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,574,951 - 32,584,336 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11532,590,652 - 32,600,343 (-)NCBI
Celera1527,551,512 - 27,560,897 (-)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Prmt5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309053
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.