Gene: Ctsa (cathepsin A) Rattus norvegicus
Symbol: Ctsa
Name: cathepsin A
Description: Predicted to have serine-type carboxypeptidase activity. Predicted to be involved in negative regulation of chaperone-mediated autophagy; proteolysis involved in cellular protein catabolic process; and regulation of protein stability. Predicted to localize to the nucleoplasm. Human ortholog(s) of this gene implicated in lysosomal storage disease. Orthologous to human CTSA (cathepsin A); PARTICIPATES IN renin-angiotensin cascade pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC296370; lysosomal protective protein; Ppgb; protective protein for beta-galactosidase
Homo sapiens (human) : CTSA (cathepsin A)  HGNC  Alliance
Mus musculus (house mouse) : Ctsa (cathepsin A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctsa (cathepsin A)
Pan paniscus (bonobo/pygmy chimpanzee) : CTSA (cathepsin A)
Canis lupus familiaris (dog) : CTSA (cathepsin A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctsa (cathepsin A)
Sus scrofa (pig) : CTSA (cathepsin A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03161,298,750 - 161,304,627 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03167,483,817 - 167,489,976 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,866,335 - 155,871,998 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13155,772,370 - 155,778,034 (+)NCBI
Celera3152,176,711 - 152,182,414 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Ctsa
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309070
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.