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Gene: Malt1 (MALT1 paracaspase) Rattus norvegicus
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Symbol: Malt1
Name: MALT1 paracaspase
Description: Predicted to contribute to kinase activator activity. Predicted to be involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of immune response; and positive regulation of macromolecule metabolic process. Predicted to localize to several cellular components, including CBM complex; fibrillar center; and polkadots. Human ortholog(s) of this gene implicated in lymphoma; non-Hodgkin lymphoma; and primary immunodeficiency disease. Orthologous to human MALT1 (MALT1 paracaspase); PARTICIPATES IN nuclear factor kappa B signaling pathway; B cell receptor signaling pathway; T cell receptor signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl; amphetamine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC307366; mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase 1; paracaspase-1; Pcasp1
Orthologs:
Homo sapiens (human) : MALT1 (MALT1 paracaspase)  HGNC  Alliance
Mus musculus (house mouse) : Malt1 (MALT1 paracaspase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Malt1 (MALT1 paracaspase)
Pan paniscus (bonobo/pygmy chimpanzee) : MALT1 (MALT1 paracaspase)
Canis lupus familiaris (dog) : MALT1 (MALT1 paracaspase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Malt1 (MALT1 paracaspase)
Sus scrofa (pig) : MALT1 (MALT1 paracaspase)
Chlorocebus sabaeus (African green monkey) : MALT1 (MALT1 paracaspase)
Heterocephalus glaber (naked mole-rat) : Malt1 (MALT1 paracaspase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01861,108,712 - 61,162,446 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1861,109,069 - 61,162,445 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01860,305,085 - 60,358,786 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41861,708,388 - 61,760,004 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11861,720,756 - 61,832,919 (+)NCBI
Celera1857,070,977 - 57,125,050 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Malt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309195
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.