Gene: Foxo3 (forkhead box O3) Rattus norvegicus
Analyze
Symbol: Foxo3
Name: forkhead box O3
Description: Exhibits transcription cofactor binding activity; involved in several processes, including aging, positive regulation of cell death, and response to steroid hormone; localizes to the cytosol, mitochondrion, and nucleus; predicted to colocalize with the mitochondrial matrix; biomarker of obesity; orthologous to human FOXO3 (forkhead box O3); PARTICIPATES IN insulin signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH (R)-lipoic acid; (R)-noradrenaline; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Fkhrl1; forkhead box O3a; forkhead box protein O3; Foxo3a; LOC294515
Orthologs:
Homo sapiens (human) : FOXO3 (forkhead box O3)  HGNC  Alliance
Mus musculus (house mouse) : Foxo3 (forkhead box O3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxo3 (forkhead box O3)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXO3 (forkhead box O3)
Canis lupus familiaris (dog) : FOXO3 (forkhead box O3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxo3 (forkhead box O3)
Sus scrofa (pig) : FOXO3 (forkhead box O3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02046,428,078 - 46,519,156 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02048,111,014 - 48,206,518 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42046,171,784 - 46,262,818 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12046,194,693 - 46,284,921 (-)NCBI
Celera2054,198,460 - 54,289,566 (+)NCBICelera
Cytogenetic Map20q12-q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Foxo3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309196
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.