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Gene: Cdt1 (chromatin licensing and DNA replication factor 1) Rattus norvegicus
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Symbol: Cdt1
Name: chromatin licensing and DNA replication factor 1
Description: Predicted to have DNA binding activity; DNA polymerase binding activity; and chromatin binding activity. Predicted to be involved in several processes, including negative regulation of cell cycle; regulation of DNA-dependent DNA replication; and regulation of protein localization to kinetochore. Predicted to localize to kinetochore and nuclear body. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Orthologous to human CDT1 (chromatin licensing and DNA replication factor 1); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA replication factor Cdt1; LOC292071; retroviral integration site 2; Ris2
Orthologs:
Homo sapiens (human) : CDT1 (chromatin licensing and DNA replication factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Cdt1 (chromatin licensing and DNA replication factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdt1 (chromatin licensing and DNA replication factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CDT1 (chromatin licensing and DNA replication factor 1)
Canis lupus familiaris (dog) : CDT1 (chromatin licensing and DNA replication factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdt1 (chromatin licensing and DNA replication factor 1)
Sus scrofa (pig) : CDT1 (chromatin licensing and DNA replication factor 1)
Chlorocebus sabaeus (African green monkey) : CDT1 (chromatin licensing and DNA replication factor 1)
Heterocephalus glaber (naked mole-rat) : Cdt1 (chromatin licensing and DNA replication factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01955,381,565 - 55,386,511 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,381,565 - 55,386,511 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,090,081 - 66,095,027 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,848,559 - 52,853,880 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,852,915 - 52,858,234 (+)NCBI
Celera1949,860,119 - 49,865,065 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cdt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309211
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.