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Gene: Tle1 (TLE family member 1, transcriptional corepressor) Rattus norvegicus
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Symbol: Tle1
Name: TLE family member 1, transcriptional corepressor
Description: Predicted to have several functions, including identical protein binding activity; repressing transcription factor binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of anoikis; negative regulation of signal transduction; and regulation of gene expression. Predicted to localize to the beta-catenin-TCF complex; cytosol; and nucleoplasm. Orthologous to human TLE1 (TLE family member 1, transcriptional corepressor); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC362533; MGC189561; transducin like enhancer of split 1; transducin-like enhancer of split 1; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 1, homolog of Drosophila E(spl); transducin-like enhancer protein 1
Orthologs:
Homo sapiens (human) : TLE1 (TLE family member 1, transcriptional corepressor)  HGNC  Alliance
Mus musculus (house mouse) : Tle1 (transducin-like enhancer of split 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tle1 (TLE family member 1, transcriptional corepressor)
Pan paniscus (bonobo/pygmy chimpanzee) : TLE1 (TLE family member 1, transcriptional corepressor)
Canis lupus familiaris (dog) : TLE1 (TLE family member 1, transcriptional corepressor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tle1 (TLE family member 1, transcriptional corepressor)
Sus scrofa (pig) : LOC100524475 (transducin-like enhancer protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0588,546,607 - 88,630,277 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0592,618,609 - 92,701,908 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4589,682,837 - 89,765,682 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1589,687,191 - 89,771,601 (-)NCBI
Celera584,643,237 - 84,725,613 (-)NCBICelera
Cytogenetic Map5q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tle1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309237
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.