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Gene: Tle1 (TLE family member 1, transcriptional corepressor) Rattus norvegicus
Symbol: Tle1
Name: TLE family member 1, transcriptional corepressor
Description: Predicted to have several functions, including identical protein binding activity; repressing transcription factor binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of anoikis; negative regulation of signal transduction; and regulation of gene expression. Predicted to localize to the beta-catenin-TCF complex; cytosol; and nucleoplasm. Orthologous to human TLE1 (TLE family member 1, transcriptional corepressor); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC362533; MGC189561; transducin like enhancer of split 1; transducin-like enhancer of split 1; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 1, homolog of Drosophila E(spl); transducin-like enhancer protein 1
Homo sapiens (human) : TLE1 (TLE family member 1, transcriptional corepressor)  HGNC  Alliance
Mus musculus (house mouse) : Tle1 (transducin-like enhancer of split 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tle1 (TLE family member 1, transcriptional corepressor)
Pan paniscus (bonobo/pygmy chimpanzee) : TLE1 (TLE family member 1, transcriptional corepressor)
Canis lupus familiaris (dog) : TLE1 (TLE family member 1, transcriptional corepressor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tle1 (TLE family member 1, transcriptional corepressor)
Sus scrofa (pig) : LOC100524475 (transducin-like enhancer protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0588,546,607 - 88,630,277 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0592,618,609 - 92,701,908 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4589,682,837 - 89,765,682 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1589,687,191 - 89,771,601 (-)NCBI
Celera584,643,237 - 84,725,613 (-)NCBICelera
Cytogenetic Map5q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Tle1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309237
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.