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Gene: Ccl12 (chemokine (C-C motif) ligand 12) Rattus norvegicus
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Symbol: Ccl12
Name: chemokine (C-C motif) ligand 12
Description: Predicted to have CCR2 chemokine receptor binding activity and chemokine activity. Involved in negative regulation of leukocyte proliferation and positive regulation of leukocyte migration. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune hypersensitivity disease (multiple); eye disease (multiple); tuberculosis (multiple); and vasculitis (multiple). Orthologous to several human genes including CCL8 (C-C motif chemokine ligand 8); PARTICIPATES IN Chagas disease pathway; chemokine mediated signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; acrylamide; amphibole asbestos.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC287562; MCP-5; monocyte chemotactic protein 5
Orthologs:
Homo sapiens (human) : CCL13 (C-C motif chemokine ligand 13)  HGNC  Alliance
Mus musculus (house mouse) : Ccl12 (chemokine (C-C motif) ligand 12)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CCL13 (C-C motif chemokine ligand 13)
Canis lupus familiaris (dog) : CCL13 (chemokine (C-C motif) ligand 13)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01069,476,866 - 69,478,416 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01069,111,876 - 69,113,426 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41070,321,036 - 70,322,586NCBIRGSC3.4rn4RGSC3.4
Celera1066,017,637 - 66,019,187 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ccl12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309255
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.