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Gene: Gli2 (GLI family zinc finger 2) Rattus norvegicus
Symbol: Gli2
Name: GLI family zinc finger 2
CRRD ID: 1309270
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; promoter-specific chromatin binding activity; and zinc ion binding activity. Involved in prostate gland development and response to mechanical stimulus. Predicted to localize to several cellular components, including axoneme; ciliary tip; and nuclear lumen. Biomarker of esophageal atresia/tracheoesophageal fistula. Human ortholog(s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Orthologous to human GLI2 (GLI family zinc finger 2); PARTICIPATES IN Hedgehog signaling pathway; basal cell carcinoma pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
Also known as: GLI-Kruppel family member GLI2; LOC304729; zinc finger protein GLI2
Homo sapiens (human) : GLI2 (GLI family zinc finger 2)  HGNC  Alliance
Mus musculus (house mouse) : Gli2 (GLI-Kruppel family member GLI2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gli2 (GLI family zinc finger 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GLI2 (GLI family zinc finger 2)
Canis lupus familiaris (dog) : GLI2 (GLI family zinc finger 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gli2 (GLI family zinc finger 2)
Sus scrofa (pig) : GLI2 (GLI family zinc finger 2)
Chlorocebus sabaeus (African green monkey) : GLI2 (GLI family zinc finger 2)
Heterocephalus glaber (naked mole-rat) : Gli2 (GLI family zinc finger 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01334,829,021 - 35,049,172 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1334,829,139 - 35,048,444 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01339,955,094 - 40,170,750 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41331,551,089 - 31,607,264 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11331,555,563 - 31,574,381 (-)NCBI
Celera1329,844,054 - 29,900,050 (-)NCBICelera
Cytogenetic Map13q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Gli2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309270
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.