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Gene: Nacc2 (NACC family member 2) Rattus norvegicus
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Symbol: Nacc2
Name: NACC family member 2
Description: Predicted to have several functions, including histone deacetylase binding activity; protein homodimerization activity; and transcription corepressor activity. Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and protein homooligomerization. Predicted to localize to the mitochondrion; nuclear chromatin; and nucleolus. Orthologous to human NACC2 (NACC family member 2); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BTB (POZ) domain containing 14A; BTB/POZ domain-containing protein 14A; Btbd14a; LOC296583; NAC-2; NACC family member 2, BEN and BTB (POZ) domain containing; nucleus accumbens associated 2, BEN and BTB (POZ) domain containing; nucleus accumbens-associated protein 2
Orthologs:
Homo sapiens (human) : NACC2 (NACC family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Nacc2 (nucleus accumbens associated 2, BEN and BTB (POZ) domain containing)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nacc2 (NACC family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NACC2 (NACC family member 2)
Canis lupus familiaris (dog) : NACC2 (NACC family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nacc2 (NACC family member 2)
Sus scrofa (pig) : NACC2 (NACC family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.033,508,084 - 3,574,787 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.038,869,877 - 8,936,580 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,237,814 - 4,301,608 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.134,238,197 - 4,270,534 (-)NCBI
Celera33,705,814 - 3,769,610 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nacc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309292
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.