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Gene: Spred2 (sprouty-related, EVH1 domain containing 2) Rattus norvegicus
Symbol: Spred2
Name: sprouty-related, EVH1 domain containing 2
Description: Predicted to have protein kinase binding activity; protein serine/threonine kinase inhibitor activity; and stem cell factor receptor binding activity. Predicted to be involved in negative regulation of cell differentiation; regulation of protein modification process; and regulation of signal transduction. Predicted to localize to cytoplasmic vesicle and plasma membrane. Orthologous to human SPRED2 (sprouty related EVH1 domain containing 2); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.
Type: protein-coding
Also known as: LOC305539; spred-2; sprouty-related, EVH1 domain-containing protein 2
Homo sapiens (human) : SPRED2 (sprouty related EVH1 domain containing 2)  HGNC  Alliance
Mus musculus (house mouse) : Spred2 (sprouty-related EVH1 domain containing 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spred2 (sprouty related EVH1 domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SPRED2 (sprouty related EVH1 domain containing 2)
Canis lupus familiaris (dog) : SPRED2 (sprouty related EVH1 domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spred2 (sprouty related EVH1 domain containing 2)
Sus scrofa (pig) : SPRED2 (sprouty related EVH1 domain containing 2)
Chlorocebus sabaeus (African green monkey) : SPRED2 (sprouty related EVH1 domain containing 2)
Heterocephalus glaber (naked mole-rat) : Spred2 (sprouty related EVH1 domain containing 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.014104,268,362 - 104,290,206 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,191,517 - 104,290,456 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014104,002,472 - 104,024,316 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414100,775,869 - 100,797,717 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.114100,717,198 - 100,818,203 (+)NCBI
Celera1493,246,801 - 93,268,145 (+)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Spred2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309304
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.