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Gene: Nek1 (NIMA-related kinase 1) Rattus norvegicus
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Symbol: Nek1
Name: NIMA-related kinase 1
Description: Predicted to have 14-3-3 protein binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including growth; regulation of DNA damage checkpoint; and response to ionizing radiation. Predicted to localize to the cytoplasm; nucleus; and pericentriolar material. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; asphyxiating thoracic dystrophy; and short-rib thoracic dysplasia 6 with or without polydactyly. Orthologous to human NEK1 (NIMA related kinase 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; chloroprene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC290705; NIMA (never in mitosis gene a)-related expressed kinase 1; NIMA (never in mitosis gene a)-related kinase 1; serine/threonine-protein kinase Nek1
Orthologs:
Homo sapiens (human) : NEK1 (NIMA related kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Nek1 (NIMA (never in mitosis gene a)-related expressed kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nek1 (NIMA related kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NEK1 (NIMA related kinase 1)
Canis lupus familiaris (dog) : NEK1 (NIMA related kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nek1 (NIMA related kinase 1)
Sus scrofa (pig) : NEK1 (NIMA related kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01632,321,010 - 32,439,421 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01631,025,718 - 31,032,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01632,155,914 - 32,274,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41632,317,987 - 32,438,010 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11632,320,904 - 32,431,386 (-)NCBI
Celera1628,993,115 - 29,112,552 (-)NCBICelera
Cytogenetic Map16p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Nek1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309375
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.