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Gene: Sucla2 (succinate-CoA ligase ADP-forming subunit beta) Rattus norvegicus
Symbol: Sucla2
Name: succinate-CoA ligase ADP-forming subunit beta
Description: Exhibits succinate-CoA ligase (ADP-forming) activity. Involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 5. Orthologous to human SUCLA2 (succinate-CoA ligase ADP-forming subunit beta); PARTICIPATES IN citric acid cycle pathway; propanoate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC361071; succinate-CoA ligase ADP-forming beta subunit; succinate-CoA ligase beta subunit; succinate-CoA ligase, ADP-forming, beta subunit; succinate-Coenzyme A ligase, ADP-forming, beta subunit; succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial
Homo sapiens (human) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Sucla2 (succinate-Coenzyme A ligase, ADP-forming, beta subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sucla2 (succinate-CoA ligase ADP-forming beta subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SUCLA2 (succinate-CoA ligase ADP-forming beta subunit)
Canis lupus familiaris (dog) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sucla2 (succinate-CoA ligase ADP-forming beta subunit)
Sus scrofa (pig) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Chlorocebus sabaeus (African green monkey) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Heterocephalus glaber (naked mole-rat) : Sucla2 (succinate-CoA ligase ADP-forming subunit beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01555,461,695 - 55,516,954 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1555,461,695 - 55,516,952 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01559,183,906 - 59,238,472 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41554,214,262 - 54,267,830 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11554,229,991 - 54,283,608 (+)NCBI
Celera1548,400,643 - 48,453,857 (+)NCBICelera
Cytogenetic Map15q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sucla2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309397
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.