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Gene: Sucla2 (succinate-CoA ligase ADP-forming subunit beta) Rattus norvegicus
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Symbol: Sucla2
Name: succinate-CoA ligase ADP-forming subunit beta
Description: Exhibits succinate-CoA ligase (ADP-forming) activity. Involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 5. Orthologous to human SUCLA2 (succinate-CoA ligase ADP-forming subunit beta); PARTICIPATES IN citric acid cycle pathway; propanoate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC361071; succinate-CoA ligase ADP-forming beta subunit; succinate-CoA ligase beta subunit; succinate-CoA ligase, ADP-forming, beta subunit; succinate-Coenzyme A ligase, ADP-forming, beta subunit; succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial
Orthologs:
Homo sapiens (human) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Sucla2 (succinate-Coenzyme A ligase, ADP-forming, beta subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sucla2 (succinate-CoA ligase ADP-forming beta subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SUCLA2 (succinate-CoA ligase ADP-forming beta subunit)
Canis lupus familiaris (dog) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sucla2 (succinate-CoA ligase ADP-forming beta subunit)
Sus scrofa (pig) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Chlorocebus sabaeus (African green monkey) : SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Heterocephalus glaber (naked mole-rat) : Sucla2 (succinate-CoA ligase ADP-forming subunit beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01555,461,695 - 55,516,954 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1555,461,695 - 55,516,952 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01559,183,906 - 59,238,472 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41554,214,262 - 54,267,830 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11554,229,991 - 54,283,608 (+)NCBI
Celera1548,400,643 - 48,453,857 (+)NCBICelera
Cytogenetic Map15q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sucla2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309397
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.