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Gene: Nlrp12 (NLR family, pyrin domain containing 12) Rattus norvegicus
Symbol: Nlrp12
Name: NLR family, pyrin domain containing 12
Description: Predicted to have ATP binding activity. Predicted to be involved in several processes, including negative regulation of cell communication; regulation of macromolecule biosynthetic process; and regulation of protein metabolic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in familial cold autoinflammatory syndrome 2. Orthologous to human NLRP12 (NLR family pyrin domain containing 12); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC292541; NACHT, leucine rich repeat and PYD containing 12; NACHT, LRR and PYD domains-containing protein 12; Nalp12
Homo sapiens (human) : NLRP12 (NLR family pyrin domain containing 12)  HGNC  Alliance
Mus musculus (house mouse) : Nlrp12 (NLR family, pyrin domain containing 12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nlrp12 (NLR family pyrin domain containing 12)
Pan paniscus (bonobo/pygmy chimpanzee) : NLRP12 (NLR family pyrin domain containing 12)
Canis lupus familiaris (dog) : LOC100855742 (NACHT, LRR and PYD domains-containing protein 12-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlrp12 (NLR family pyrin domain containing 12)
Sus scrofa (pig) : NLRP12 (NLR family pyrin domain containing 12)
Chlorocebus sabaeus (African green monkey) : NLRP12 (NLR family pyrin domain containing 12)
more info ...
Allele / Splice: Nlrp12em1Mcwi  
Genetic Models: SS-Nlrp12em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0164,506,750 - 64,543,908 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl164,506,735 - 64,534,912 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0163,493,575 - 63,521,356 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4164,242,875 - 64,271,212 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1164,320,985 - 64,349,047 (+)NCBI
Celera163,663,350 - 63,691,368 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nlrp12
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309415
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.