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Gene: Det1 (DET1 partner of COP1 E3 ubiquitin ligase) Rattus norvegicus
Symbol: Det1
Name: DET1 partner of COP1 E3 ubiquitin ligase
Description: Predicted to have protein binding activity, bridging involved in substrate recognition for ubiquitination and ubiquitin protein ligase binding activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and protein-containing complex assembly. Predicted to localize to the Cul4A-RING E3 ubiquitin ligase complex. Orthologous to human DET1 (DET1 partner of COP1 E3 ubiquitin ligase); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2-methoxyethanol; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
Also known as: de-etiolated homolog 1; de-etiolated homolog 1 (Arabidopsis); DET1 homolog; DET1, COP1 ubiquitin ligase partner; LOC308775; MGC116189; RGD1309793; similar to RIKEN cDNA 2610034H20
Homo sapiens (human) : DET1 (DET1 partner of COP1 E3 ubiquitin ligase)  HGNC  Alliance
Mus musculus (house mouse) : Det1 (de-etiolated homolog 1 (Arabidopsis))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Det1 (DET1 partner of COP1 E3 ubiquitin ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : DET1 (DET1 partner of COP1 E3 ubiquitin ligase)
Canis lupus familiaris (dog) : DET1 (DET1 partner of COP1 E3 ubiquitin ligase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Det1 (DET1 partner of COP1 E3 ubiquitin ligase)
Sus scrofa (pig) : DET1 (DET1 partner of COP1 E3 ubiquitin ligase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01140,519,755 - 140,535,969 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01141,494,829 - 141,511,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41134,552,235 - 134,566,070 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11134,627,799 - 134,653,445 (-)NCBI
Celera1124,823,167 - 124,836,180 (-)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Det1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309793
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.