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Gene: Dmpk (DM1 protein kinase) Rattus norvegicus
Symbol: Dmpk
Name: DM1 protein kinase
CRRD ID: 1309825
Description: Predicted to have ATP binding activity; myosin phosphatase regulator activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including muscle cell apoptotic process; regulation of skeletal muscle contraction; and regulation of synapse structural plasticity. Localizes to membrane. Human ortholog(s) of this gene implicated in myotonic dystrophy type 1. Orthologous to human DMPK (DM1 protein kinase); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5-triiodo-L-thyronine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Dm15; dystrophia myotonica kinase, B15; dystrophia myotonica-protein kinase; LOC308405; myotonin-protein kinase
Homo sapiens (human) : DMPK (DM1 protein kinase)  HGNC  Alliance
Mus musculus (house mouse) : Dmpk (dystrophia myotonica-protein kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dmpk (DM1 protein kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : DMPK (DM1 protein kinase)
Canis lupus familiaris (dog) : DMPK (DM1 protein kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dmpk (DM1 protein kinase)
Sus scrofa (pig) : DMPK (DM1 protein kinase)
Chlorocebus sabaeus (African green monkey) : DMPK (DM1 protein kinase)
Heterocephalus glaber (naked mole-rat) : Dmpk (DM1 protein kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0179,988,096 - 79,999,358 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,989,019 - 79,999,364 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,257,000 - 81,267,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,449,324 - 78,450,578 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1178,518,239 - 78,529,227 (+)NCBI
Celera173,194,993 - 73,206,254 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Dmpk
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309825
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-09-15
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.