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Gene: Sh3pxd2b (SH3 and PX domains 2B) Rattus norvegicus
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Symbol: Sh3pxd2b
Name: SH3 and PX domains 2B
Description: Predicted to have SH2 domain binding activity; phosphatidylinositol phosphate binding activity; and superoxide-generating NADPH oxidase activator activity. Predicted to be involved in several processes, including animal organ development; osteoblast fate commitment; and podosome assembly. Predicted to localize to cytoplasm and podosome. Human ortholog(s) of this gene implicated in Frank-Ter Haar syndrome. Orthologous to human SH3PXD2B (SH3 and PX domains 2B); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC303021; RGD1309926; SH3 and PX domain-containing protein 2B; similar to RIKEN cDNA G431001E03 gene
Orthologs:
Homo sapiens (human) : SH3PXD2B (SH3 and PX domains 2B)  HGNC  Alliance
Mus musculus (house mouse) : Sh3pxd2b (SH3 and PX domains 2B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh3pxd2b (SH3 and PX domains 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : SH3PXD2B (SH3 and PX domains 2B)
Canis lupus familiaris (dog) : SH3PXD2B (SH3 and PX domains 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh3pxd2b (SH3 and PX domains 2B)
Sus scrofa (pig) : SH3PXD2B (SH3 and PX domains 2B)
Chlorocebus sabaeus (African green monkey) : SH3PXD2B (SH3 and PX domains 2B)
Heterocephalus glaber (naked mole-rat) : Sh3pxd2b (SH3 and PX domains 2B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01017,209,152 - 17,296,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,209,212 - 17,291,876 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,104,796 - 17,192,048 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41017,184,256 - 17,265,186 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1016,569,377 - 16,655,161 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Sh3pxd2b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309926
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.