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Gene: Sh3pxd2b (SH3 and PX domains 2B) Rattus norvegicus
Symbol: Sh3pxd2b
Name: SH3 and PX domains 2B
Description: Predicted to have SH2 domain binding activity; phosphatidylinositol phosphate binding activity; and superoxide-generating NADPH oxidase activator activity. Predicted to be involved in several processes, including animal organ development; osteoblast fate commitment; and podosome assembly. Predicted to localize to cytoplasm and podosome. Human ortholog(s) of this gene implicated in Frank-Ter Haar syndrome. Orthologous to human SH3PXD2B (SH3 and PX domains 2B); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC303021; RGD1309926; SH3 and PX domain-containing protein 2B; similar to RIKEN cDNA G431001E03 gene
Homo sapiens (human) : SH3PXD2B (SH3 and PX domains 2B)  HGNC  Alliance
Mus musculus (house mouse) : Sh3pxd2b (SH3 and PX domains 2B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh3pxd2b (SH3 and PX domains 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : SH3PXD2B (SH3 and PX domains 2B)
Canis lupus familiaris (dog) : SH3PXD2B (SH3 and PX domains 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh3pxd2b (SH3 and PX domains 2B)
Sus scrofa (pig) : SH3PXD2B (SH3 and PX domains 2B)
Chlorocebus sabaeus (African green monkey) : SH3PXD2B (SH3 and PX domains 2B)
Heterocephalus glaber (naked mole-rat) : Sh3pxd2b (SH3 and PX domains 2B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01017,209,152 - 17,296,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,209,212 - 17,291,876 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,104,796 - 17,192,048 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41017,184,256 - 17,265,186 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1016,569,377 - 16,655,161 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Sh3pxd2b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309926
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.