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Gene: Sim1 (SIM bHLH transcription factor 1) Rattus norvegicus
Symbol: Sim1
Name: SIM bHLH transcription factor 1
CRRD ID: 1309949
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to be involved in regulation of transcription by RNA polymerase II and ureteric bud development. Predicted to localize to nuclear chromatin. Human ortholog(s) of this gene implicated in obesity. Orthologous to human SIM1 (SIM bHLH transcription factor 1); INTERACTS WITH bisphenol A; gentamycin; vinclozolin.
Type: protein-coding
Also known as: LOC309888; MGC189161; single-minded 1; single-minded family bHLH transcription factor 1; single-minded homolog 1; single-minded homolog 1 (Drosophila)
Homo sapiens (human) : SIM1 (SIM bHLH transcription factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Sim1 (single-minded family bHLH transcription factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sim1 (SIM bHLH transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIM1 (SIM bHLH transcription factor 1)
Canis lupus familiaris (dog) : SIM1 (SIM bHLH transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sim1 (SIM bHLH transcription factor 1)
Sus scrofa (pig) : SIM1 (SIM bHLH transcription factor 1)
Chlorocebus sabaeus (African green monkey) : SIM1 (SIM bHLH transcription factor 1)
Heterocephalus glaber (naked mole-rat) : Sim1 (SIM bHLH transcription factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02055,590,810 - 55,674,002 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2055,594,676 - 55,673,995 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02057,192,734 - 57,274,564 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42054,908,178 - 54,988,099 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12054,937,202 - 55,012,573 (+)NCBI
Celera2046,257,466 - 46,336,238 (-)NCBICelera
Cytogenetic Map20q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Sim1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309949
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.