Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tlr1 (toll-like receptor 1) Rattus norvegicus
Symbol: Tlr1
Name: toll-like receptor 1
Description: Exhibits lipopeptide binding activity. Involved in microglial cell activation; response to bacterial lipoprotein; and toll-like receptor signaling pathway. Predicted to localize to Golgi apparatus; Toll-like receptor 1-Toll-like receptor 2 protein complex; and membrane raft. Biomarker of perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; aspergillosis; asthma; leprosy; and pyelonephritis. Orthologous to human TLR1 (toll like receptor 1); PARTICIPATES IN Toll-like receptor signaling pathway; INTERACTS WITH 3-chloropropane-1,2-diol; 4,4'-diaminodiphenylmethane; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC305354; rCG56938-like
Homo sapiens (human) : TLR1 (toll like receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Tlr1 (toll-like receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr1 (toll like receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TLR1 (toll like receptor 1)
Canis lupus familiaris (dog) : TLR1 (toll like receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlr1 (toll like receptor 1)
Sus scrofa (pig) : TLR1 (toll like receptor 1)
Chlorocebus sabaeus (African green monkey) : TLR1 (toll like receptor 1)
Heterocephalus glaber (naked mole-rat) : Tlr1 (toll like receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01445,062,662 - 45,065,014 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1445,062,662 - 45,081,991 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,871,931 - 44,874,283 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41446,114,913 - 46,124,820 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1442,538,240 - 42,540,804 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Tlr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309975
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.