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Gene: Tlr1 (toll-like receptor 1) Rattus norvegicus
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Symbol: Tlr1
Name: toll-like receptor 1
Description: Exhibits lipopeptide binding activity. Involved in microglial cell activation; response to bacterial lipoprotein; and toll-like receptor signaling pathway. Predicted to localize to Golgi apparatus; Toll-like receptor 1-Toll-like receptor 2 protein complex; and membrane raft. Biomarker of perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; aspergillosis; asthma; leprosy; and pyelonephritis. Orthologous to human TLR1 (toll like receptor 1); PARTICIPATES IN Toll-like receptor signaling pathway; INTERACTS WITH 3-chloropropane-1,2-diol; 4,4'-diaminodiphenylmethane; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC305354; rCG56938-like
Orthologs:
Homo sapiens (human) : TLR1 (toll like receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Tlr1 (toll-like receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr1 (toll like receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TLR1 (toll like receptor 1)
Canis lupus familiaris (dog) : TLR1 (toll like receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlr1 (toll like receptor 1)
Sus scrofa (pig) : TLR1 (toll like receptor 1)
Chlorocebus sabaeus (African green monkey) : TLR1 (toll like receptor 1)
Heterocephalus glaber (naked mole-rat) : Tlr1 (toll like receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01445,062,662 - 45,065,014 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1445,062,662 - 45,081,991 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,871,931 - 44,874,283 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41446,114,913 - 46,124,820 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1442,538,240 - 42,540,804 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tlr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1309975
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.