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Gene: Foxl2 (forkhead box L2) Rattus norvegicus
Symbol: Foxl2
Name: forkhead box L2
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; estrogen receptor binding activity; and ubiquitin conjugating enzyme binding activity. Predicted to be involved in several processes, including animal organ development; positive regulation of gonadotropin secretion; and regulation of transcription by RNA polymerase II. Predicted to localize to intercellular bridge and nucleoplasm. Human ortholog(s) of this gene implicated in blepharophimosis, ptosis, and epicanthus inversus syndrome and premature ovarian failure. Orthologous to human FOXL2 (forkhead box L2); INTERACTS WITH all-trans-retinoic acid; mono(2-ethylhexyl) phthalate; oxybenzone.
Type: protein-coding
RefSeq Status: MODEL
Also known as: forkhead box protein L2; LOC367152
Homo sapiens (human) : FOXL2 (forkhead box L2)  HGNC  Alliance
Mus musculus (house mouse) : Foxl2 (forkhead box L2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxl2 (forkhead box L2)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC103782957 (uncharacterized LOC103782957)
Canis lupus familiaris (dog) : FOXL2 (forkhead box L2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxl2 (forkhead box L2)
Sus scrofa (pig) : FOXL2 (forkhead box L2)
Chlorocebus sabaeus (African green monkey) : FOXL2 (forkhead box L2)
Heterocephalus glaber (naked mole-rat) : Foxl2 (forkhead box L2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08107,194,492 - 107,197,644 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,194,551 - 107,195,675 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08106,618,909 - 106,622,004 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,804,019 - 103,805,239 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18103,818,892 - 103,825,932 (+)NCBI
Celera898,919,088 - 98,922,240 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Foxl2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310041
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.