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Gene: Adamts16 (ADAM metallopeptidase with thrombospondin type 1 motif, 16) Rattus norvegicus
Symbol: Adamts16
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 16
Description: Predicted to have metalloendopeptidase activity. Involved in male gamete generation; regulation of cilium assembly; and regulation of systemic arterial blood pressure. Used to study cryptorchidism; hypertension; and male infertility. Orthologous to human ADAMTS16 (ADAM metallopeptidase with thrombospondin type 1 motif 16); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 4-hydroxyphenyl retinamide (ortholog); aflatoxin B1 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A disintegrin and metalloproteinase with thrombospondin motifs 16; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16; LOC306664
Allele / Splice: Adamts16em1Bj  
Genetic Models: SS-Adamts16em1Bj
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0135,067,268 - 35,200,530 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0136,468,949 - 36,599,799 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4172,559,771 - 2,690,663 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1172,390,909 - 2,689,575 (+)NCBI
Celera131,055,382 - 31,178,973 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Adamts16
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310046
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.