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Gene: Adamts16 (ADAM metallopeptidase with thrombospondin type 1 motif, 16) Rattus norvegicus
Symbol: Adamts16
Name: ADAM metallopeptidase with thrombospondin type 1 motif, 16
Description: Predicted to have metalloendopeptidase activity. Involved in male gamete generation; regulation of cilium assembly; and regulation of systemic arterial blood pressure. Used to study cryptorchidism; hypertension; and male infertility. Orthologous to human ADAMTS16 (ADAM metallopeptidase with thrombospondin type 1 motif 16); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 4,4'-sulfonyldiphenol (ortholog); 4-hydroxyphenyl retinamide (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A disintegrin and metalloproteinase with thrombospondin motifs 16; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16; LOC306664
Allele / Splice: Adamts16em1Bj  
Genetic Models: SS-Adamts16em1Bj
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0135,067,268 - 35,200,530 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl135,067,490 - 35,198,939 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0136,468,949 - 36,599,799 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4172,559,771 - 2,690,663 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1172,390,909 - 2,689,575 (+)NCBI
Celera131,055,382 - 31,178,973 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Adamts16
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310046
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.