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Gene: Gmps (guanine monophosphate synthase) Rattus norvegicus
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Symbol: Gmps
Name: guanine monophosphate synthase
CRRD ID: 1310063
Description: Exhibits GMP synthase activity and enzyme binding activity. Involved in GMP biosynthetic process; response to L-cysteine; and response to drug. Localizes to cytosol. Biomarker of hepatocellular carcinoma. Orthologous to human GMPS (guanine monophosphate synthase); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glutamine amidotransferase; GMP synthase; GMP synthase [glutamine-hydrolyzing]; GMP synthetase; guanine monophosphate synthetase; LOC295088
Orthologs:
Homo sapiens (human) : GMPS (guanine monophosphate synthase)  HGNC  Alliance
Mus musculus (house mouse) : Gmps (guanine monophosphate synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gmps (guanine monophosphate synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : GMPS (guanine monophosphate synthase)
Canis lupus familiaris (dog) : GMPS (guanine monophosphate synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gmps (guanine monophosphate synthase)
Sus scrofa (pig) : GMPS (guanine monophosphate synthase)
Chlorocebus sabaeus (African green monkey) : GMPS (guanine monophosphate synthase)
Heterocephalus glaber (naked mole-rat) : Gmps (guanine monophosphate synthase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02154,555,967 - 154,590,662 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2154,555,871 - 154,590,662 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02173,939,844 - 173,974,539 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42153,804,512 - 153,840,009 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12153,754,474 - 153,789,970 (+)NCBI
Celera2142,726,833 - 142,761,299 (+)NCBICelera
Cytogenetic Map2q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gmps
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310063
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.