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Gene: Pycr2 (pyrroline-5-carboxylate reductase 2) Rattus norvegicus
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Symbol: Pycr2
Name: pyrroline-5-carboxylate reductase 2
Description: Predicted to have pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process and cellular response to oxidative stress. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 10. Orthologous to human PYCR2 (pyrroline-5-carboxylate reductase 2); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; INTERACTS WITH acetamide; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC364064; P5C reductase 2; P5CR 2; pyrroline-5-carboxylate reductase family, member 2
Orthologs:
Homo sapiens (human) : PYCR2 (pyrroline-5-carboxylate reductase 2)  HGNC  Alliance
Mus musculus (house mouse) : Pycr2 (pyrroline-5-carboxylate reductase family, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pycr2 (pyrroline-5-carboxylate reductase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PYCR2 (pyrroline-5-carboxylate reductase 2)
Canis lupus familiaris (dog) : PYCR2 (pyrroline-5-carboxylate reductase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pycr2 (pyrroline-5-carboxylate reductase 2)
Sus scrofa (pig) : PYCR2 (pyrroline-5-carboxylate reductase 2)
Chlorocebus sabaeus (African green monkey) : PYCR2 (pyrroline-5-carboxylate reductase 2)
Heterocephalus glaber (naked mole-rat) : Pycr2 (pyrroline-5-carboxylate reductase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01399,184,624 - 99,188,418 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1399,184,564 - 99,188,431 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013104,182,905 - 104,186,734 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41396,633,455 - 96,637,249 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11396,822,390 - 96,826,184 (+)NCBI
Celera1392,171,198 - 92,174,992 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pycr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310074
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.