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Gene: Dhx58 (DEXH-box helicase 58) Rattus norvegicus
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Symbol: Dhx58
Name: DEXH-box helicase 58
Description: Predicted to have double-stranded RNA binding activity; single-stranded RNA binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including negative regulation of innate immune response; regulation of type I interferon production; and regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway. Predicted to localize to the cytoplasm. Orthologous to human DHX58 (DExH-box helicase 58); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DEXH (Asp-Glu-X-His) box polypeptide 58; Lgp2; LOC303538; probable ATP-dependent RNA helicase DHX58; RGD1310093; RNA helicase LGP2; similar to hypothetical protein FLJ11354
Orthologs:
Homo sapiens (human) : DHX58 (DExH-box helicase 58)  HGNC  Alliance
Mus musculus (house mouse) : Dhx58 (DEXH (Asp-Glu-X-His) box polypeptide 58)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dhx58 (DExH-box helicase 58)
Pan paniscus (bonobo/pygmy chimpanzee) : DHX58 (DExH-box helicase 58)
Canis lupus familiaris (dog) : DHX58 (DExH-box helicase 58)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dhx58 (DExH-box helicase 58)
Sus scrofa (pig) : DHX58 (DExH-box helicase 58)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01088,599,722 - 88,611,562 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,599,680 - 88,611,105 (-)Ensembl
Rnor_5.01088,393,935 - 88,405,328 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,630,145 - 89,641,311 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11089,644,843 - 89,655,680 (-)NCBI
Celera1084,336,054 - 84,347,209 (-)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dhx58
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310093
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.