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Gene: Hook2 (hook microtubule-tethering protein 2) Rattus norvegicus
Symbol: Hook2
Name: hook microtubule-tethering protein 2
Description: Predicted to have dynein light intermediate chain binding activity; identical protein binding activity; and microtubule binding activity. Predicted to be involved in several processes, including cytoskeleton-dependent intracellular transport; early endosome to late endosome transport; and endosome to lysosome transport. Predicted to colocalize with the HOPS complex. Orthologous to human HOOK2 (hook microtubule tethering protein 2); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hook homolog 2; hook homolog 2 (Drosophila); LOC304669
Homo sapiens (human) : HOOK2 (hook microtubule tethering protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Hook2 (hook microtubule tethering protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hook2 (hook microtubule tethering protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HOOK2 (hook microtubule tethering protein 2)
Canis lupus familiaris (dog) : HOOK2 (hook microtubule tethering protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hook2 (hook microtubule tethering protein 2)
Sus scrofa (pig) : HOOK2 (hook microtubule tethering protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01926,106,713 - 26,119,353 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01937,082,361 - 37,094,976 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,808,204 - 24,819,397 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11924,813,376 - 24,824,426 (-)NCBI
Celera1922,709,747 - 22,721,741 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Hook2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310171
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.