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Gene: Hook2 (hook microtubule-tethering protein 2) Rattus norvegicus
Symbol: Hook2
Name: hook microtubule-tethering protein 2
CRRD ID: 1310171
Description: Predicted to have dynein light intermediate chain binding activity; identical protein binding activity; and microtubule binding activity. Predicted to be involved in several processes, including cytoplasmic microtubule organization; early endosome to late endosome transport; and endosome to lysosome transport. Predicted to colocalize with HOPS complex. Orthologous to human HOOK2 (hook microtubule tethering protein 2); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hook homolog 2; hook homolog 2 (Drosophila); LOC304669
Homo sapiens (human) : HOOK2 (hook microtubule tethering protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Hook2 (hook microtubule tethering protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hook2 (hook microtubule tethering protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HOOK2 (hook microtubule tethering protein 2)
Canis lupus familiaris (dog) : HOOK2 (hook microtubule tethering protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hook2 (hook microtubule tethering protein 2)
Sus scrofa (pig) : HOOK2 (hook microtubule tethering protein 2)
Chlorocebus sabaeus (African green monkey) : HOOK2 (hook microtubule tethering protein 2)
Heterocephalus glaber (naked mole-rat) : Hook2 (hook microtubule tethering protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01926,106,713 - 26,119,353 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1926,106,838 - 26,119,352 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01937,082,361 - 37,094,976 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,808,204 - 24,819,397 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11924,813,376 - 24,824,426 (-)NCBI
Celera1922,709,747 - 22,721,741 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Hook2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310171
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.