Gene: Xrn2 (5'-3' exoribonuclease 2) Rattus norvegicus
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Symbol: Xrn2
Name: 5'-3' exoribonuclease 2
Description: Predicted to have 3'-5'-exoribonuclease activity, 5'-3' exonuclease activity, and transcription termination site sequence-specific DNA binding activity; involved in hippocampus development, neuron differentiation, and retina development in camera-type eye; localizes to the nucleus; biomarker of status epilepticus; orthologous to human XRN2 (5'-3' exoribonuclease 2); PARTICIPATES IN 3'-end pre-mRNA processing pathway; ribosome biogenesis pathway; RNA polymerase II transcription termination pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC362229
Orthologs:
Homo sapiens (human) : XRN2 (5'-3' exoribonuclease 2)  HGNC  Alliance
Mus musculus (house mouse) : Xrn2 (5'-3' exoribonuclease 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xrn2 (5'-3' exoribonuclease 2)
Pan paniscus (bonobo/pygmy chimpanzee) : XRN2 (5'-3' exoribonuclease 2)
Canis lupus familiaris (dog) : XRN2 (5'-3' exoribonuclease 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xrn2 (5'-3' exoribonuclease 2)
Sus scrofa (pig) : XRN2 (5'-3' exoribonuclease 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03141,224,858 - 141,298,272 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03147,641,256 - 147,716,287 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43135,651,059 - 135,724,442 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13135,541,370 - 135,629,673 (+)NCBI
Celera3133,299,770 - 133,372,470 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Xrn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310218
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.