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Gene: Mff (mitochondrial fission factor) Rattus norvegicus
Symbol: Mff
Name: mitochondrial fission factor
CRRD ID: 1310230
Description: Exhibits GTPase binding activity. Involved in several processes, including cellular response to hydrogen peroxide; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of cellular component organization. Localizes to synaptic vesicle. Colocalizes with mitochondrial membrane and synaptic vesicle membrane. Used to study transient cerebral ischemia. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human MFF (mitochondrial fission factor); PARTICIPATES IN mitochondria fission pathway; INTERACTS WITH bisphenol A; chloroprene; cocaine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC301563; MGC112646; mitochondrial fission factor-like; RGD1310230; similar to RIKEN cDNA 5230400G24; uncharacterized protein LOC100911613
Homo sapiens (human) : MFF (mitochondrial fission factor)  HGNC  Alliance
Mus musculus (house mouse) : Mff (mitochondrial fission factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mff (mitochondrial fission factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MFF (mitochondrial fission factor)
Canis lupus familiaris (dog) : MFF (mitochondrial fission factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mff (mitochondrial fission factor)
Sus scrofa (pig) : MFF (mitochondrial fission factor)
Chlorocebus sabaeus (African green monkey) : MFF (mitochondrial fission factor)
Heterocephalus glaber (naked mole-rat) : Mff (mitochondrial fission factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0988,490,280 - 88,518,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl988,493,593 - 88,517,827 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0988,237,923 - 88,266,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4982,045,236 - 82,071,135 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1982,226,339 - 82,254,116 (+)NCBI
Celera981,449,284 - 81,477,522 (+)NCBICelera
Cytogenetic Map9q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Mff
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310230
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.