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Gene: Mff (mitochondrial fission factor) Rattus norvegicus
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Symbol: Mff
Name: mitochondrial fission factor
Description: Exhibits GTPase binding activity. Involved in several processes, including positive regulation of cardiac muscle cell apoptotic process; positive regulation of cellular component organization; and protein targeting to mitochondrion. Localizes to the synaptic vesicle. Colocalizes with the mitochondrial membrane and synaptic vesicle membrane. Used to study transient cerebral ischemia. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human MFF (mitochondrial fission factor); PARTICIPATES IN mitochondria fission pathway; INTERACTS WITH bisphenol A; chloroprene; cocaine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC301563; MGC112646; mitochondrial fission factor-like; RGD1310230; similar to RIKEN cDNA 5230400G24; uncharacterized protein LOC100911613
Orthologs:
Homo sapiens (human) : MFF (mitochondrial fission factor)  HGNC  Alliance
Mus musculus (house mouse) : Mff (mitochondrial fission factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mff (mitochondrial fission factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MFF (mitochondrial fission factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mff (mitochondrial fission factor)
Sus scrofa (pig) : MFF (mitochondrial fission factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0988,490,280 - 88,518,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0988,237,923 - 88,266,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4982,045,236 - 82,071,135 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1982,226,339 - 82,254,116 (+)NCBI
Celera981,449,284 - 81,477,522 (+)NCBICelera
Cytogenetic Map9q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mff
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310230
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.