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Gene: Nfx1 (nuclear transcription factor, X-box binding 1) Rattus norvegicus
Symbol: Nfx1
Name: nuclear transcription factor, X-box binding 1
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of MHC class II biosynthetic process and negative regulation of transcription by RNA polymerase II. Predicted to localize to the cytosol; nuclear lumen; and plasma membrane. Orthologous to human NFX1 (nuclear transcription factor, X-box binding 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC313166; transcriptional repressor NF-X1
Homo sapiens (human) : NFX1 (nuclear transcription factor, X-box binding 1)  HGNC  Alliance
Mus musculus (house mouse) : Nfx1 (nuclear transcription factor, X-box binding 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfx1 (nuclear transcription factor, X-box binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NFX1 (nuclear transcription factor, X-box binding 1)
Canis lupus familiaris (dog) : NFX1 (nuclear transcription factor, X-box binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfx1 (nuclear transcription factor, X-box binding 1)
Sus scrofa (pig) : NFX1 (nuclear transcription factor, X-box binding 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0557,290,916 - 57,348,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,291,156 - 57,348,720 (+)Ensembl
Rnor_5.0561,822,485 - 61,879,030 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4558,366,449 - 58,424,124 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1558,366,721 - 58,408,789 (+)NCBI
Celera554,717,075 - 54,774,576 (+)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nfx1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310277
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.