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Gene: Nfx1 (nuclear transcription factor, X-box binding 1) Rattus norvegicus
Symbol: Nfx1
Name: nuclear transcription factor, X-box binding 1
CRRD ID: 1310277
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of MHC class II biosynthetic process; negative regulation of transcription by RNA polymerase II; and protein autoubiquitination. Predicted to localize to cytosol; nuclear lumen; and plasma membrane. Orthologous to human NFX1 (nuclear transcription factor, X-box binding 1); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC313166; transcriptional repressor NF-X1
Homo sapiens (human) : NFX1 (nuclear transcription factor, X-box binding 1)  HGNC  Alliance
Mus musculus (house mouse) : Nfx1 (nuclear transcription factor, X-box binding 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfx1 (nuclear transcription factor, X-box binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NFX1 (nuclear transcription factor, X-box binding 1)
Canis lupus familiaris (dog) : NFX1 (nuclear transcription factor, X-box binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfx1 (nuclear transcription factor, X-box binding 1)
Sus scrofa (pig) : NFX1 (nuclear transcription factor, X-box binding 1)
Chlorocebus sabaeus (African green monkey) : NFX1 (nuclear transcription factor, X-box binding 1)
Heterocephalus glaber (naked mole-rat) : Nfx1 (nuclear transcription factor, X-box binding 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0557,290,916 - 57,348,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,291,156 - 57,348,720 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0561,822,485 - 61,879,030 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4558,366,449 - 58,424,124 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1558,366,721 - 58,408,789 (+)NCBI
Celera554,717,075 - 54,774,576 (+)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nfx1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310277
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.