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Gene: Itga3 (integrin subunit alpha 3) Rattus norvegicus
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Symbol: Itga3
Name: integrin subunit alpha 3
Description: Exhibits several functions, including fibronectin binding activity; integrin binding activity; and protein heterodimerization activity. Involved in several processes, including maternal process involved in female pregnancy; positive regulation of epithelial cell migration; and regulation of cell projection organization. Localizes to several cellular components, including the growth cone filopodium; integrin alpha3-beta1 complex; and perinuclear region of cytoplasm. Biomarker of glomerulonephritis and myocardial infarction. Orthologous to human ITGA3 (integrin subunit alpha 3); PARTICIPATES IN altered Reelin signaling pathway; integrin mediated signaling pathway; Reelin signaling pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: integrin alpha 3 ; integrin alpha-3; integrin, alpha 3; LOC360606
Orthologs:
Homo sapiens (human) : ITGA3 (integrin subunit alpha 3)  HGNC  Alliance
Mus musculus (house mouse) : Itga3 (integrin alpha 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga3 (integrin subunit alpha 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA3 (integrin subunit alpha 3)
Canis lupus familiaris (dog) : ITGA3 (integrin subunit alpha 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga3 (integrin subunit alpha 3)
Sus scrofa (pig) : ITGA3 (integrin subunit alpha 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01082,855,841 - 82,887,755 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01082,666,856 - 82,698,319 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,728,710 - 83,759,576 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11083,744,399 - 83,774,825 (-)NCBI
Celera1078,763,866 - 78,796,174 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Itga3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310333
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.