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Gene: Irf5 (interferon regulatory factor 5) Rattus norvegicus
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Symbol: Irf5
Name: interferon regulatory factor 5
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific DNA binding activity. Predicted to be involved in several processes, including defense response to virus; response to muramyl dipeptide; and response to peptidoglycan. Predicted to localize to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in inflammatory bowel disease 14 and systemic lupus erythematosus. Orthologous to human IRF5 (interferon regulatory factor 5); PARTICIPATES IN Toll-like receptor signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC296953
Orthologs:
Homo sapiens (human) : IRF5 (interferon regulatory factor 5)  HGNC  Alliance
Mus musculus (house mouse) : Irf5 (interferon regulatory factor 5)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : IRF5 (interferon regulatory factor 5)
Canis lupus familiaris (dog) : IRF5 (interferon regulatory factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irf5 (interferon regulatory factor 5)
Sus scrofa (pig) : IRF5 (interferon regulatory factor 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0456,804,477 - 56,816,271 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0456,571,823 - 56,583,434 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,407,560 - 56,418,694 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1456,666,980 - 56,677,876 (+)NCBI
Celera453,236,000 - 53,247,024 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Irf5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1310447
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.